The Fayez Sarofim Lymphoma Center
Our principle areas of pediatric lymphoma research focus on understanding the genetic determinants of tumor biology, exploiting the relationship of lymphoma with the immune system to develop immunotherapy, and in new drug development.
We are part of a National Cancer Institute-funded Specialized Programs of Research Excellence (SPORE) grant and participate in Children’s Oncology Group (COG) and internal lymphoma studies within Texas Children’s Cancer Center and the Cell and Gene Therapy Program.
The Lymphoma Program at Texas Children’s Cancer Center is dedicated to the integration of laboratory and clinical research to increase our understanding of lymphoma and to develop new, more effective therapies for these conditions.
Stephen Gottschalk, MD – PTLD, Chronic Active EBV (CAEBV) – Immunotherapy for virus-associated malignancies and diseases using cytotoxic T lymphocytes (CTLs). Lymphoma research focused on Epstein-Barr virus positive lymphomas.
Helen Heslop, MD – As a Co-Director of the CTL Program, Dr. Heslop is actively researching anti-viral and anti-tumor immunity following transplant. She is also the principal investigator for the Specialized Program of Research Excellence in Lymphoma
Terzah Horton, MD, PhD – Identification of molecular defects contributing to leukemia and lymphoma, including Hodgkin’s lymphoma. Proteomics and the deregulation of cell cycle protein degradation during malignancy development.
Cliona Rooney, PhD – As a Co-Director of the CTL Program, Dr. Rooney is exploring options to improve immunotherapies for virus-associated diseases and malignancies using cytotoxic T lymphocytes (CTLs).