Texas Children's Cancer & Hematology Centers

Bone Marrow Failure Program

The Bone Marrow Failure Program at Texas Children's Hematology Center

As experts in the care of childhood bone marrow failure, our patients receive quality care at one of the nation’s best hospitals. As part of Texas Children’s Hematology Center, the Bone Marrow Failure Program diagnoses and treats a variety of conditions associated with bone marrow failure.  

Conditions that result in bone marrow failure are extremely rare.  The Bone Marrow Failure Program has extensive experience in diagnosing and treating children with bone marrow failure, with approximately 20 new patients seeking care at our center each year, and approximately 60 patients receiving ongoing care.

Some of the conditions we treat include:

  • Acquired aplastic anemia, including hepatitis-associated
  • Barth syndrome
  • Congenital amegakaryocytic thrombocytopenia
  • Diamond Blackfan anemia
  • Dyskeratosis congenita
  • Fanconi anemia
  • Myelodysplastic syndrome
  • Myelofibrosis
  • RUNX1 deficiency syndrome
  • Severe congenital neutropenia (Kostmann syndrome)
  • Shwachman Diamond syndrome
  • Thrombocytopenia-absent radius syndrome

We perform bone marrow aspirations and biopsies with the assistance of the Texas Children’s Hospital Anesthesiology Service.  Child life specialists are available to speak with patients before their bone marrow evaluations, which allows patients to understand these procedures at an age-appropriate level.

We provide a comprehensive and timely approach to diagnosis and treatment, and work closely with our hematopathologists and clinical cytogeneticists to offer state-of-the-art care.

Patients with acquired aplastic anemia are able to receive treatment in the form of immunosuppressive therapy through our Bone Marrow Failure program.
Our patients with inherited bone marrow failure syndromes, as well as acquired aplastic anemia, benefit from our expert Bone Marrow Transplantation Program, which provides optimal therapy for these disorders.  The Bone Marrow Transplant Program has the largest pediatric transplant unit in the Southwest United States. Patients who undergo a bone marrow transplant for bone marrow failure benefit from a state-of-the art HEPA air-filtration system that allows them to leave their rooms, making them more comfortable during their treatment.

As a part of one of the best children’s hospitals in the nation, our program is able to provide multidisciplinary care for every patient, to provide the best quality of care. 

Our clinic is located at Texas Children’s Hospital, in the world-renowned Texas Medical Center. Outpatient treatment and transfusions are given in our patient and family-friendly clinic environment, while more extensive procedures may require a longer hospitalization.