Cancer Cytogenetics Core Laboratory
Texas Children’s Cancer Center
Department of Pediatrics
Section of Hematology-Oncology
Baylor College of Medicine
Pulivarthi Rao, Ph.D.
1102 Bates Street, Suite 1030.16
Houston, TX 77030
The main goal of Dr. Pulivarthi Rao’s laboratory is the analysis of the genetic basis of deregulation of cellular proliferation and differentiation associated with malignant transformation. The laboratory staff investigates several tumor types, most notably osteosarcoma and multiple myeloma. A wide range of functional, comparative and diagnostic cytogenetic techniques is utilized in these studies, which include conventional and molecular cytogenetics- FISH, comparative genomic hybridization (CGH), multicolor spectral karyotyping (SKY), and array CGH. The laboratory emphasizes the investigation of the relevance of newly discovered genetic markers to tumor classification and clinical stratification of patients. His laboratory is also focusing on the development of molecular cytogenetic techniques for the analysis of chromosomal aberrations in murine models of human cancers (Comparative Cancer Cytogenetics).
Learn more about the Cancer Cytogenetics Core Laboratory.
Ph.D., Nagarjuna University, India
Post-doc, Department of Human Genetics, Memorial Sloan Kettering Cancer Center
Clinical Laboratory Cytogenetics Director License – New York State Department of Health
Member, American Society for Human Genetics
Member, American Association for Advancement of Science
Member, American Association for Cancer Research (AACR)
Genetic basis of deregulation of cellular proliferation
Differentiation associated with malignant transformation