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Date:August 12, 2012

Nino Rainusso, M.D.

Nino Rainusso, M.D.Assistant Professor
Department of Pediatrics
Section of Hematology-Oncology
Baylor College of Medicine

Dr. Nino Rainusso
6701 Fannin Street, Suite 1510
Houston, TX 77030

Phone: 832-822-4242
Fax: 832-825-1453
Email: ncrainuss@txch.org

Biography

Dr. Nino Rainusso, is an assistant professor of pediatrics – hematology/oncology at Baylor College of Medicine and Texas Children’s Cancer and Hematology Centers. He is a board-certified pediatric hematologist-oncologist specializing in the care of children with sarcomas.

Dr. Rainusso obtained his M.D. degree from Universidad Peruana Cayetano Heredia (Lima, Peru) in 2000. He completed his residency in pediatrics at University of Illinois at Chicago and a fellowship in pediatric hematology-oncology as part of the combined Baylor College of Medicine/Texas Children’s Hospital program. In addition, of the three years of pediatric hematology/oncology fellowship, he completed one year specialized fellowship focusing on pediatric sarcomas.

His research focuses in the role of cancer stem cells in the development and progression of pediatric sarcomas. Dr. Rainusso has been awarded numerous honors for his research, including the American Society of Clinical Oncology Young Investigator Award (2009). He is a St. Baldrick’s Scholar and has received funding from the Snowdrop Foundation, the St. Baldrick’s Foundation, the American Society of Clinical Oncology and the Children’s Cancer Research Fund to support his work.

Dr. Nino Rainusso is a member of the Bone Tumor Program and the Musculoskeletal Tumor Clinic Team at Texas Children’s Cancer and Hematology Centers.

Education

M.D., Universidad Peruana Cayetano Heredia (Lima,Peru)
Residency, University of Illinois at Chicago
Fellowship, Baylor College of Medicine/Texas Children’s Hospital

Board Certifications

American Board of Pediatrics
American Board of Pediatrics – Hematology/Oncology

Selected Memberships

Member, American Association for Cancer Research (AACR)
Member, American Society of Clinical Oncology (ASCO)
Member, American Society for Pediatric Hematology/Oncology (ASPHO)
Member, Sarcoma Foundation of America (SFA)

Clinical Interests

Osteosarcoma, Ewing’s sarcoma, rhabdomyosarcoma

Research Interests

Identification and complete genomic characterization of cancer stem cells in pediatric sarcomas

Research

Dr. Rainusso is conducting research under the mentorship of Dr. Jeffrey Rosen in close collaboration with Dr. Jason Yustein. The goal of his translational research is to isolate, molecularly characterize and target cancer stem cells in pediatric sarcomas. Cancer stem cells are characterized by their self-renewal, quiescence and increased migratory capacities, which are key inherent features for tumor initiation and metastatic progression. Moreover, cancer stem cells are particularly resistant to the effects of some anticancer drugs and radiation therapy. Therefore, the combination of conventional treatments with the development of novel cancer stem cell-specific therapies would significantly impact patient treatment outcomes.

Dr. Rainusso is using novel genetically engineered mouse models of osteosarcoma and rhabdomyosarcoma, the two most common sarcomas in children, to isolate cancer stem cells. Additionally, he plans to utilize a patient-derived tumor xenograft transplantation (PDTX) model to study cancer stem biology in sarcomas and to evaluate tumor response using different anti-cancer drugs.