Date:July 26, 2012

Cliona Rooney, PhD

Cliona Rooney. Ph.D.Professor
Department of Pediatrics, Section of Hematology-Oncology,
Department of Molecular Virology and Microbiology, and
Department of Immunology
Baylor College of Medicine

Cliona Rooney, PhD
1102 Bates Street, Suite 1570
Houston, TX 77030

Phone: 832-824-4693
Fax: 832-825-4732
Email: cmrooney@txch.org

About Cliona Rooney, PhD

Dr. Cliona Rooney’s research interests are immunotherapies for virus and non-virus-associated malignancies and diseases. In protocols developed with Dr. Helen Heslop, Dr. Malcolm Brenner, Dr. Stephen Gottschalk and Dr. Catherine Bollard, about 150 patients have received EBV or antigen-specific cytotoxic T-cells. These have prevented and cured EBV-associated lymphoma in BMT recipients produced mixed tumor responses, including complete remissions in patients with relapsed EBV-positive Hodgkin’s disease and nasopharyngeal carcinoma and have produced clinical remission in chronic-active EBV infections. In the research laboratory, she is developing methods for the activation and expansion of antigen-specific CTLs for the treatment of non-viral cancers, investigating ways to render CTL resistant to immune evasion strategies used by tumor cells to grow in an immunocompetent host and developing means to induce antigen-specific tolerance.

Dr. Cliona Rooney is a member of the Center for Cell and Gene Therapy (CAGT)

Learn about the Research Laboratory of Cliona Rooney

Education

Ph.D., University of Cambridge, England
Post-doc, University of Bristol, England
Post-doc, University of Birmingham, England
Post-doc, Yale University

Professional Organizations

Member, International Association for EBV and Associated Malignant Diseases
Member, American Society of Gene Therapy (ASGT)
Member, American Society of Virology (ASV)
Member, New York Academy of Sciences (NYAS)

Research Activities

Immunotherapies for virus and non-virus-associated malignancies
EBV, antigen-specific cytotoxic T-cells
Treatment of non-viral cancers
Induction of antigen-specific tolerance