Date:March 08, 2013

Carl Allen, MD, PhD

Carl Allen, M.D., Ph.D.Co-Director, Histiocytosis Program
Texas Children’s Cancer Center

Co-Director, Lymphoma Program
Texas Children’s Cancer Center

Associate Professor
Department of Pediatrics
Section of Hematology-Oncology
Baylor College of Medicine

Dr. Carl Allen
1102 Bates Street, Suite 750.01
Houston, TX 77030

832-824-4312
FAX: 832-825-1206
ceallen@txch.org

About Carl Allen, MD, PhD

Along with Dr. Kenneth McClain, Dr. Carl Allen has developed the largest Histiocytosis Center in the world with over 100 new diagnoses annually.

Dr. Allen graduated from Ohio State University College of Medicine and Public Health with his medical degree and doctorate of philosophy. He completed his resident at Columbus Children’s Hospital and pediatric hematology-oncology fellowship at Baylor College of Medicine.

His clinical special interests include: Langerhans cell histiocytosis (LCH), hemophagocytic lymphohistiocytosis (HLH), leukemia, lymphoma and stem cell transplantation.

He is board certified by the American Board of Pediatrics in pediatric hematology/oncology and a member of the Leukemia Program and co-director of the Lymphoma Program.

Research

Dr. Carl Allen’s primary research is focused on the clinical and biologic aspects of Langerhans cell histiocytosis (LCH). Along with Dr. Kenneth McClain, Dr. Carl Allen has developed the largest Histiocytosis Center in the world with over 100 new diagnoses annually, allowing the center to create a large bank of LCH tissues and plasma.

Dr. Allen has developed gene expression and proteomic strategies to analyze the identity and function of the cells that cause LCH. The ultimate goal of these experiments is to identify genes, proteins, and pathways that may be used to diagnose and cure patients with LCH. These experiments may also provide insight into dendritic cell biology and tumor immunology.

Dr. Carl Allen is an associate professor of pediatric hematology-oncology at Baylor College of Medicine (BCM). He is co-director of the Fayez Sarofim Lymphoma Program research laboratory at Texas Children’s Cancer and Hematology Centers. Dr. Allen has significant experience in clinical as well as translational research. He is principal investigator of investigator-initiated clinical trials in Hodgkin lymphoma and non-Hodgkin lymphoma, both of which include correlative biology aims. He is national principal investigator of a study to optimize hematopoietic cell transplant in patients with EBV-related lymphoproliferative disorders, through the Blood and Marrow Transplant Clinical Trials Network.

Dr. Allen has an ongoing collaborative research effort with the Uganda Cancer Institute research program, and collects tissue (viably preserved tumor, peripheral blood cells and plasma) and linked clinical data on approximately 25 new endemic Burkitt’s Lymphoma cases every quarter from Uganda.

His research interests include: Langerhans cell histiocytosis (LCH), hemophagocytic lymphohistiocytosis (HLH), lymphoma, tumor immunology, lymphocyte development and dendritic cell biology.

Education

MD, Ohio State University College of Medicine and Public Health
PhD, Ohio State University College of Medicine and Public Health
Residency, Columbus Children’s Hospital
Fellowship, Baylor College of Medicine

Professional Organizations

Member, Histiocyte Society
Member, American Society for Pediatric Hematology/Oncology (ASPHO)
Member, American Society of Clinical Oncology (ASCO)
Member, American Society of Hematology (ASH)
Member, American Society of Bone Marrow Transplantation (ASBMT)