About the Bone Tumor Program
As one of the largest programs in the country, the Bone Tumor Program at Texas Children’s Cancer Center offers multidisciplinary care to patients with bone tumors including osteosarcoma and Ewing sarcoma.
Our team of experts in pediatric bone tumors includes pediatric oncologists, orthopedic oncologic surgeons, physical therapists, pediatric pathologists, musculoskeletal radiologists, pediatric nurses, social workers and child life specialists. This team approach enables patients and families to receive the most comprehensive and innovative care in a single location over the full course of their treatment and follow-up.
Evaluation and treatment
Patients with bone lesions, whether suspected or known to be malignant, receive initial evaluation in our multidisciplinary Musculoskeletal Tumor Clinic where they are seen by both a pediatric oncologist and an orthopedic oncology surgeon. Patients with malignant bone tumors will receive care and treatment from this unique team of providers at Texas Children’s Cancer Center; patients with benign bone tumors receive follow up care from the Department of Orthopedics at Texas Children’s Hospital. Modalities of treatment used to treat malignant bone tumors may include surgery, chemotherapy, radiation therapy and/or immunotherapy.
Texas Children’s Cancer Center has the largest and most comprehensive bone tumor research program in the United States. The program is designed to integrate the work of laboratory researchers and translational researchers with clinicians who are directly involved in the care of patients with bone tumors. The common goal is to discover more effective, less toxic treatments for bone tumor patients.
Bone tumor research investigators have ongoing studies focused on understanding the pathogenesis, biology and malignant determinants of bone tumors. A major aim is to develop novel approaches that will prevent the development of metastases.
About Bone Tumors
Bone tumors account for approximately 6% of malignancies in the pediatric population. The most common forms of bone tumors that arise in the bone are osteosarcoma and Ewing sarcoma. Osteosarcoma arises from bone cells and is more common in older teenagers, whereas Ewing sarcoma arises from neural crest cells and tends to occur in younger children. Ewing sarcoma belongs to a larger family known as the Ewing Sarcoma Family of Tumors (ESFT) that can arise in other tissues of the body as well as in the bone. In almost all cases, the cause of these tumors is not known, but there is much research being conducted to try to understand factors that initiate these tumors and allow them to progress in order to find better treatments. Both tumors are curable and are treated by a combination of chemotherapy, surgery +/- radiation therapy. This requires an integrated team of caregivers that includes pediatric oncology, general surgery, orthopedic surgery and radiation oncology.
The most common malignant bone tumors in children and adolescents are osteosarcoma and Ewing sarcoma. Patients with these tumors require multidisciplinary care from a team of providers that includes pediatric oncology, orthopedic oncologic surgery, physical therapy, pathologists and radiologists with expertise in bone diseases, specialized nursing care, as well as pediatric social workers and child life specialists. The Bone Tumors Program provides all of these services to our patients.
Patients with bone lesions, whether suspected or known to be malignant, will receive initial evaluation in our Musculoskeletal Tumor Clinic by both a pediatric oncologist and orthopedic surgeon. Patients with benign bone tumors will receive follow up care in close follow-up with the Orthopedic Service at Texas Children’s Hospital. Patients with malignant bone tumors will receive care from the Bone Tumor Program at Texas Children’s Cancer Center, the hematology-oncology treatment center of Texas Children’s Hospital.
Donate to the Bone Tumor Program
Donations to support the Bone Tumor Program may be made online. Please make sure to specify under ‘Comments’ that the donation is for the Bone Tumor Program.