About the Childhood Cancer Prevention and Screening Clinic
The Childhood Cancer Prevention and Screening Clinic is a first of its kind clinic that provides centralized cancer screening services for children with hereditary cancer predisposition syndromes and other conditions that increase the risk of childhood cancer.
Our pediatric oncologist develops and implements screening regimens adapted for each child based on the latest medical literature. Screenings consist of longitudinal assessments including interviews, physical exams, laboratory testing, and imaging. With a dedicated staff, we provide the most effective and up-to-date screening methods available to children at risk of developing childhood cancer.
Cancer Screening Methods
The screening regimens we are implementing for these at-risk children include serial clinical interviews, physical exams, laboratory tests, imaging studies, and other subspecialist evaluations. The methods are based on the latest medical evidence and are adapted to the needs of each child. In children whom we find pre-malignant lesions and tumors, these screenings are enabling early intervention and treatment, and ultimately are leading to improved survival and decreased treatment-related chronic health issues.
Conditions we treat
We are following children with the following syndromes and conditions:
- Beckwith-Wiedemann Syndrome / Isolated Hemihypertrophy
- Bannayan-Riley-Ruvalcaba Syndrome
- Biallelic mismatch repair gene mutations
- Costello Syndrome
- Cowden Syndrome
- DICER1-related Pleuropulmonary Blastoma Family Tumor and Dysplasia Syndrome
- Familial Adenomatous Polyposis
- Hereditary Leiomyomatosis and Renal Cell Cancer
- Hereditary Paraganglioma-Pheochromocytoma Syndrome
- Li-Fraumeni Syndrome
- Multiple Endocrine Neoplasia, Type 1
- Multiple Endocrine Neoplasia, Type 2
- Nevoid Basal Cell Carcinoma (Gorlin) Syndrome
- Peutz-Jeghers Syndrome
- Rhabdoid Predisposition Syndrome
- Tuberous Sclerosis Complex
- Von Hippel-Lindau Disease
- Paraneoplastic syndromes with concern for occult malignancy
- Other rare syndromes/conditions in which cancer risk is greatly elevated and screening may improve outcomes
Families interested in being seen in our clinic are encouraged to talk to their primary medical providers. After the initial visit is completed, we will provide a letter to the referring provider summarizing the child’s cancer risks and our management plan. For children whom we continue to provide long-term cancer screening services, primary medical providers will receive ongoing status updates and recommendations on their patients.