Pediatric Cancer Genetics Research

Pediatric Hematology-Oncology Research

State-of-the art research, breakthrough treatments

Texas Children's Cancer Center Cancer Genetics Program combines cancer research with a clinic that translates research progress into useful information for patient families and their physicians.

Cancer Genetics Research Program
Research Program Director	Sharon Plon, M.D., Ph.D.
Research Laboratories	Alison Bertuch, M.D., Ph.D. Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells; the role of telomere biology in tumorigensis and bone marrow failure Debananda Pati, Ph.D. Chromosomal cohesion and separation and their role in the development of aneuploidy, tumorigenesis and regulation of apoptotic cell death. Sharon Plon, M.D., Ph.D. Cancer predisposition syndromes; the molecular basis of genomic instability in cancers Lisa Wang, M.D. Bone tumors and cancer predisposition syndromes, specifically Rothmund-Thomson syndrome (RTS).

Cancer Genetics Research Program

Research Program Director

Sharon Plon, M.D., Ph.D.

Research Laboratories

Alison Bertuch, M.D., Ph.D.
Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells; the role of telomere biology in tumorigensis and bone marrow failure

Debananda Pati, Ph.D.
Chromosomal cohesion and separation and their role in the development of aneuploidy, tumorigenesis and regulation of apoptotic cell death.

Sharon Plon, M.D., Ph.D.
Cancer predisposition syndromes; the molecular basis of genomic instability in cancers

Lisa Wang, M.D.
Bone tumors and cancer predisposition syndromes, specifically Rothmund-Thomson syndrome (RTS).

Recent Initiatives

The Cancer Genetics Program of Baylor College of Medicine and Texas Children's Cancer Center is studying Rothmund-Thomson Syndrome in order to better understand the molecular basis of cancers.